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Artemether and Lumefantrine Powder for Suspension

Brands: SQ-Antiria; Oral Preparation; Drug Class: Antimalaria
Specification/Dosage: 180mg+1080mg/60ml
Packaging: 60ml bottle/box, 100ml bottle/box

SQ-Antiria(artemether and lumefantrine) Uses:

SQ-Antiria contains artemether and lumefantrine as active ingredients.

Artemether and lumefantrine powder for suspension are the generic form of the brand-name drug SQ-Antiria, a drug indicated in the treatment of various types of malaria. Artemether in this product is a derivative of artemisinin, which has a powerful and rapid killing effect on the plasmodium erythrocytic phase and can quickly control clinical onset and symptoms. Artemisinin changes its membranous structure by affecting the ultrastructure of the plasmodium erythropolis. Due to the function of the food bubble membrane, the malarial nutrient uptake was blocked. When the Plasmodium lost a large amount of cytoplasm and nutrients and was not supplemented, it quickly died. lumefantrine can kill Plasmodium erythrozoic schizonts and kill insects more thoroughly. The cure rate is about 95%, but it is not effective for pre-erythrocytic and gametophyte.

Artemether is easily absorbed after oral administration, and plasma concentration reaches its peak after 30 minutes. It is widely distributed in the body, with the most brain tissue, followed by the liver and kidney. It is excreted mainly through the intestines, followed by urinary excretion. Oral absorption of lumefantrine is slow, and the plasma concentration peaks 4 to 5 hours after administration. The residence time in the body is long and t1/2 is 24 to 72 hours.

Artemether and Lumefantrine Powder for Suspension use for child

This product has a slight side effect. Aspartate aminotransferase and alanine aminotransferase were slightly elevated in only few patients.

Phenobarbital induces demethylation of the product, which increases metabolism.

Active Ingredients: Artemether 180mg and Lumefantrine 1080mg
Dossier: ACTD, CTD or According client requirement
Shelf life: 3years(36 months)
Manufacturers(factory) made in China

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Brands: SQ-Antiria; Oral Preparation; Drug Class: Antimalaria