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Chloramphenicol Capsule

Brands: S.Q-Chlonicol;Oral Preparation;Drug Class: Antibiotics
Specification/Dosage: 250mg
Packaging: 10 capsules x 1 blister/box, 10 capsules x 2 blister/box; 10 x 10 blisters/box; Others

S.Q-Chlonicol(Chloramphenicol) Uses:

Chloramphenicol capsules is the generic form of the brand-name drug S.Q-Chlonicol, a drug indications are

  • Typhoid fever and other salmonella infections: the drug of choice for typhoid fever and paratyphoid caused by susceptible strains. Gastroenteritis caused by Salmonella infection is generally not suitable for this product. If the condition is serious, it may be used when combined sepsis is possible; In adult typhoid and paratyphoid Salmonella infections, fluoroquinolones are preferred (pregnant women and children should not use such drugs).
  • Ampicillin-resistant Haemophilus influenzae type B meningitis or Streptococcus pneumoniae in patients with penicillin allergy, Neisseria meningitis meningitis, and sensitive Gram-negative bacillus meningitis, this product can be used as one of the selected drugs.
  • Brain abscess, especially otogenic, is often a combination of aerobic and anaerobic bacteria.
  • Severe anaerobic infections, such as those caused by Bacteroides fragilis, are particularly suitable for those with lesions involving the central nervous system. They can be used in combination with aminoglycoside antibiotics for the treatment of abdominal infections and pelvic infections to control the presence of both aerobic and anaerobic bacteria. infection.
  • No other low-toxic antibacterial drugs can replace various serious infections caused by sensitive bacteria, such as sepsis caused by Haemophilus influenzae, Salmonella and other gram-negative bacilli, and lung infections, often with aminoglycosides. Combined use; 6. Rickettsia infection can be used for the treatment of Q fever, spotty Rocky Mountains, and endemic typhus.

Other Information

  • Active Ingredients: Chloramphenicol 250mg
  • Standard: USP, BP,CP
  • Dossier: ACTD, CTD or According client requirement
  • Shelf life: 3 years(36 months)

The toxic reaction to the hematopoietic system is the most serious adverse effect of chloramphenicol.
Hemolytic anemia can occur in patients with certain congenital glucose-6-phosphate dehydrogenase deficiency.
Long-term treatment with this product can induce blood propensity, which may be related to myelosuppression, inhibition of vitamin K synthesis caused by decreased intestinal flora, and prolonged prothrombin time.
Peripheral neuritis and optic neuritis often occur during long-term treatment. Early withdrawal is often reversible, and optic nerve atrophy occurs and blindness occurs.
Gastrointestinal reaction may have diarrhea, nausea, vomiting and so on.
Double infection can cause lung, gastrointestinal, and urinary tract infections such as Proteus, Pseudomonas aeruginosa, Staphylococcus aureus, and fungi.

Due to the possibility of irreversible myelosuppression, this product should avoid repeated treatment.
Patients with impaired liver and kidney function should avoid the use of this product, such as the need to reduce the use of the application, when the conditions of blood concentration monitoring, the peak concentration (Cmax) below 25mg / L, trough concentration below 5mg / L . If the plasma concentration exceeds this range, the risk of bone marrow suppression may increase.
When taken orally, the product should be taken on an empty stomach, ie, taken 1 hour before or 2 hours after the meal, in order to achieve effective plasma concentrations.
Interference with Diagnosis: When urinary glucose is measured using the copper sulphate method, false-positive reactions may occur in patients with chloramphenicol.

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