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Norfloxacin Tablets

Brands: S.Q-Norfcin; Oral Preparation; Drug Class: Antibacterial
Specification/Dosage: 100mg, 400mg
Packaging: 10 tablets x 1 blister/box, 10 tablets x 2 blister/box, 10 tablets x 3 blisters/box, 10 tablets x 10 blisters/box, Others

SQ-Norfcin(Norfloxacin)Uses:

Norfloxacin tablet is the generic form of the brand-name drug S.Q-Norfcin, a drug used to treat indications are acute and chronic pyelonephritis, cystitis, prostatitis, bacterial dysentery, cholecystitis, typhoid fever, prenatal and postpartum infections, pelvic inflammatory disease, otitis media, sinusitis, acute tonsillitis and skin caused by sensitive bacteria. Soft tissue infections can also be used as preventive drugs for celiac surgery.

Side effect:

  • Gastrointestinal reactions are more common and may manifest as abdominal discomfort or pain, diarrhea, nausea, or vomiting.
  • Central nervous system reactions can cause dizziness, headache, drowsiness, or insomnia.
  • Allergic reactions Skin rash, pruritus, occasional exudative erythema and angioedema. A few patients have photosensitivity reactions.
  • Occasionally: seizures, mental disorders, irritability, disturbance of consciousness, hallucinations, tremor, hematuria, fever, rash, interstitial nephritis, phlebitis, crystalline urine, joint pain.
  • A small number of patients may have elevated serum aminotransferase, increased blood urea nitrogen, and decreased peripheral blood leukocytes, which are mostly mild and transient.

Warning:

  • Patients who are allergic to this product and fluoroquinolones are disabled.
  • Due to the current prevalence of E. coli resistant to norfloxacin, urine specimens should be cultured prior to administration. Refer to the results of bacterial susceptibility adjustments.
  • This product can be used in large doses or urine pH value of 7 or more when crystalline urine can occur. In order to avoid the occurrence of crystalline urine, it is advisable to drink more water and maintain a urine output of 1200 ml or more for 24 hours.
  • In patients with impaired renal function, the dosage should be adjusted according to renal function.
  • Application of fluoroquinolones can produce moderate and severe photosensitivity reactions. When using this product, excessive exposure to sunlight should be avoided. If photosensitized reaction occurs, it should be stopped.

Interactions:

  • Alkalizing agent can reduce the solubility of this product in urine, resulting in crystalline urine and nephrotoxicity.
  • The combination of cyclosporine and this product can increase the blood concentration of the former. It is necessary to monitor the blood concentration of cyclosporine and adjust the dose.
  • When used together with anticoagulant warfarin, this product can enhance the anticoagulant effect of the latter, and the prothrombin time of the patient should be closely monitored when used together.
  • Probenecid can reduce the secretion of this product from the renal tubules by about 50%, and when combined, it can cause toxicity due to the increased blood concentration of the product.
  • This product is antagonistic to nitrofurantoin and is not recommended for combination use.

Other Information

  • Active Ingredients: Norfloxacin 100mg, 400mg
  • Standard: USP; BP; CP
  • Dossier: ACTD, CTD or According client requirement
  • Shelf life: 3 years(36 months)
  • Manufacturers(factory) made in China